Increases in use of methotrexate since the 1980s.
نویسنده
چکیده
In this chapter, we review the use of DMARDs in several clinical RA cohorts and databases between the 1970s and the 2000s. The DMARD profile in the QUEST-RA database provides an overview of clinical use of MTX in recent years in 25 countries. The data show that (I) MTX is currently the most frequently used DMARD in RA, and (II) that this development has taken about 20 years to emerge.
منابع مشابه
Comparison of Two Therapeutic Regimens: Methotrexate-Folinic Acid (8 days) and Weekly Methotrexate in Patients with Low risk Gestational Trophoblastic neoplasia
Background: Methotrexate is used in the treatment of Low-risk Gestational Trophoblastic Neoplasia. The purpose of this study was to compare the therapeutic responses and side effects of two therapeutic methods which were prescribed for patients suffering from Low-risk Gestational Trophoblastic Neoplasia. One method was the daily use of Methotrexate-Folic Acid (for 8 da...
متن کاملبررسی تاثیر تجویز متوترکسات در آسم وابسته به کورتیکواستروئید
Despite the role of oral corticosteroids in management of sever asthma, use of these drugs needs careful awareness of its many side effects. There are controversies about the role of methotrexate in lowering the need for corticosteroides in these patients. In this study an attempt has been made to determine methotrexate effects in corticosteroid dependent asthma. Six patients were entered in a ...
متن کاملهپاتوتوکسیسیتی متوتروکسات؛ خطری که نباید نادیده گرفته شود: معرفی 4 بیمار و مرور مطالب کاربردی
Introduction: Methotrexate is used increasingly for treatment of some diseases such as rheumatoid arthritis, psoriasis and Crohn. Bone marrow suppression, mucocutaneous lesions, pneumonitis, and hepatotoxicity are major side effects of this drug. Since methotrexate toxicity is dose dependent and is usually administered with low dose via a weekly regimen, its side effects are not commonly seen. ...
متن کاملTreatment of Severe Alopecia Areata Using Methotrexate as an Adjunctive Drug in Combination with Intravenous and Oral Corticosteroid
Background: Alopecia areata is one of the most common human autoimmune disorders and its severe types are refractory to all conventional therapies. Corticosteroids have been used in severe alopecia areata since 1950s but there is concern over complications caused by high doses of corticosteroids. Methotrexate has been used as an adjunctive therapy in some autoimmune disorders and has been propo...
متن کاملEvolution of the female roles in the US (Case study: The Hollywood movies in the late 1970s and early 1980s)
Prior to the 1980s, numerous charges of discrimination were noteworthy among women in Hollywood. In those years, women were in uncertain situations, so they seemed aimless and vulnerable. In the period that this article focuses on, the female characters are or have become intelligent and therefore open-minded and potentially independent. Although, they are still vulnerable and unsure of themsel...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Clinical and experimental rheumatology
دوره 28 5 Suppl 61 شماره
صفحات -
تاریخ انتشار 2010